Researchers are developing a dental implant that automatically spews precise amounts of time-released drugs for individuals with diabetes, hypertension, and other diseases. Devised by the Fraunhofer Institute for Biomedical Technologies, the Intellidrug implant contains a drug reservoir, valve, sensors and actuators yet fits inside two faux molars. A wireless transmitter lets the patient know when the teeth need a refill. The dosage can also be remotely adjusted. The first clinical trials will begin soon, using a medication to help drug addicts kick addiction. From The Engineer:
'It is important for some conditions that there is a constant level of drug in the blood plasma,' said (researcher Thomas) Velten. 'Also, for people at risk from heart attacks, these attacks commonly take place very early in the morning when the patient is asleep and cannot self-medicate. With this system we can time the dosage to take place – even when the patient is sleeping…'
Once the device is fitted, saliva in the mouth enters the reservoir via a membrane and dissolves the solid drug, forming a solution. When the system is triggered, a valve opens and allows a controlled amount of this saturated solution to flow into the mouth where it is then absorbed by the mucous membranes in the patient's cheeks.
