We've posted before about researchers exploring slime molds as a kind of bio-computer capable of some amazing accomplishments in information processing. Recently, computer scientist Andrew Adamtzky of the University of the West of England in Bristol and his colleagues used a slime mold to devise optimal interstate highway systems for the United States, Britain, Mexico, Brazil, the Netherlands, and Canada (above). He will detail his latest slime systems in a forthcoming issue of the scientific journal Complex Systems, "devoted to the science, mathematics, and engineering of systems with simple components but complex overall behavior." For a teaser, check out Adamatzky's recent op-ed in the New York Times, titled "The Wisdom of Slime."