Kliph Nesteroff wrote a long article for WFMU's blog about Cary Grants' LSD experiences.
Cary Grant was the first mainstream celebrity to espouse the virtues of psychedelic drugs. Whereas novelist Aldous Huxley's famous 1954 treatise The Doors of Perception recounted his remarkable experiences with mescaline, Huxley was hardly mainstream – a darling of intellectual circles to be sure, but a far cry from a matinee idol. Grant was one of the biggest stars Hollywood had to offer when he jumped headlong into Huxley's Heaven and Hell. His endorsement of subconscious exploration, arguably, created more interest in LSD than Dr. Timothy Leary who was largely preaching to the converted. Grant on the other hand was the fantasy of countless Midwestern women. He convinced wholesome movie starlets like Esther Williams and Dyan Cannon to blow their minds. When Ladies Home Journal and Good Housekeeping interviewed him, the topic of conversation wasn't Cary's favorite recipe or "the problem with youth today." Instead, Cary Grant was telling happy homemakers that LSD was the greatest thing in the world.