The program guide for TED 2010 is up and, as usual, the speakers are interesting. Highlights, for me, include ukulele player Jake Shimabukuro (do yourself a favor and watch some of Jake's YouTube videos), neuroscientist Sam Harris, 4chan founder Christopher "moot" Poole, David Byrne, spider silk scientist Cheryl Hayashi, and Wisdom of Whores author Elizabeth Pisani.