Wikipedia has a sterling list of curse-words and other expletives that were made up for use in works of fiction:
* arsegike from 2000 AD, a corruption of arsehole (coined accidentally by Simon Spurrier when using usenet and used in his strips ever since – if you attempt to write the letters HOL with your fingers shifted one letter to the left on a QWERTY keyboard, the result is GIK.).
* ASCII from ReBoot, used by Matrix to Ray Tracer. Used in the same way as “ass”, as in “Cover my ASCII, what are you?”
* ass-tard From Andy Weir’s webcomic Casey and Andy, a portmanteau of “bastard,” “ass” and “retard,” and used in the same way as its source words.
* ass-clown- an insult made up by Mike Judge off the top of his head to describe singer Michael Bolton for a particular line of the film “Office Space” so as not to have to call him a “no talent ass-hole” . Also used again in the film Bad Santa by the same man who played Samir in “Office Space”. Frequently used by wrestler Chris Jericho.
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(via Making Light)