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Infectious wellness

A modified ebola strain is being tested as a delivery system for gene-therapy:

While replacing the infection-causing genes inside an ordinarily harmful retrovirus with helpful genetic material is a relatively common research practice, David Sanders and his colleagues have gone a step beyond this technique.

The group, which also includes Anthony Sanchez of the Centers for Disease Control and Purdue graduate student Scott Jeffers, has hit upon a way to simplify Ebola’s outer shell as well, rendering it more easily produced in a laboratory and more effective at delivering genes to defective cells. Since unmodified Ebola enters through, and attacks, the lungs, defective lung cells could benefit most from therapy based on this discovery.

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(Thanks, John!)

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